Suggested Use: 1-6 capsules per day, in divided doses, with meals.
Niacinamide (vitamin B3) is a precursor of nicotinamide adeninedinucleotide (NAD), essential for oxidation-reduction reactions, nutrient metabolism and ATP synthesis. It does not cause the vasodilatation ("flush") associated with niacin.
What Is It?
Niacinamide (vitamin B3) supports energy metabolism,
metabolic function and joint comfort. It does not cause
the vasodilatation (“flush”) associated with niacin.*
Uses For Niacinamide
Energy Production: Niacinamide is a precursor of nicotinamide
adenine dinucleotide (NAD), essential for oxidationreduction
reactions, nutrient metabolism and ATP
synthesis. Alpha lipoic acid offers additional support for
the energy production process.*
Glucose Metabolism: Research indicates that niacinamide
may support healthy glucose metabolism and protect
pancreatic beta cell function. In a meta-analysis of 10
randomized controlled trials, niacinamide supplementation
promoted healthy C-peptide levels, insulin
metabolism and beta cell function. In another study,
niacinamide helped maintain healthy C-peptide levels,
HbA1c and glucose metabolism. Alpha lipoic acid is
included to offer synergistic support for healthy glucose
balance and metabolic function.*
Joint Function: Niacinamide promotes joint mobility and
comfort as well. In a 12-week randomized double blind
trial involving 72 subjects, niacinamide provided statistically
significant support for joint flexibility and normal
What Is The Source?
Niacinamide and alpha lipoic acid are synthetic. Hypoallergenic
plant fiber is derived from pine cellulose.
Pure Encapsulations recommends 1-6 capsules daily, in
divided doses, with meals.
Are There Any Potential Side Effects Or
If pregnant or lactating, consult your physician before
taking this product. There have been reports of GI upset,
nausea, vomiting, heartburn, diarrhea, dizziness, drowsiness
or headache with large doses of niacinamide. Rarely,
niacinamide in doses of 3 grams/day or more has been
associated with elevated liver function tests. Consult your
physician for more information.
Are There Any Potential Drug Interactions?
There are case reports in the literature indicating that
niacinamide may reduce the hepatic metabolism of
primidone and carbamazepine. Individuals taking these
medications should consult their physician. Individuals
taking anti-diabetes medications should have their blood
glucose levels monitored. Consult your physician for