Suggested Use: Adults: Take 3 tablets twice
daily at least 45 minutes before meals with water.
Wobenzym® PS -
Enzymes are biological catalysts that are critical
and necessary to support life. Every second, there
are 15,000 enzymes guiding 30 quadrillion chemical
reactions within our bodies. Whether it's breathing,
growing, digestion, energy production, nerve impulses
or immune balance, all of life's actions are directed by
For over 60 years, Wobenzym® has been a trusted
name for systemic enzyme supplementation.
Developed by leading scientists and used by
millions of people worldwide, the family of
Wobenzym® products has proven to be safe and
useful for overall immune support. Wobenzym PS in
particular has numerous clinical studies that link its
use to maintaining optimal joint health.
In the human body, hundreds of chemical
reactions occur during the course of normal
metabolic processes. Many chemical reactions
require significant energy in order to take place,
and therefore need a catalyst to allow the
reaction to proceed. The catalyst acts to lower
the energy needed for the reaction to move
forward. In the body, enzymes play the role of
the catalyst and allow reactions to take place
that otherwise would not occur. The enzyme
itself is not consumed in this process and can be
utilized again and again. Enzymes are relatively
unique to each reaction and different enzymes
will catalyze different reactions. Structurally,
enzymes are complex molecules that are
comprised of amino acid chains and can
sometimes include co-factors which assist the
enzyme in the chemical reaction. Some
enzymes are sensitive to changes in pH and
temperature and can be destroyed if exposed to
less than ideal conditions.
Wobenzym® PS is a systemic enzyme formulation
that contains a unique blend of enzymes from both
plants and animals that haves been clinically
studied for supporting numerous processes in the
Systemic enzyme supplements work directly
in the body after they are absorbed in the small
intestine, and are not intended to aid in digestion.
Consequently, these enzymes can be utilized to
assist the body's various regulatory and
Click to See Systemic Enzyme Support Protocol Information
After the enzymes are absorbed, protease
molecules can bind with molecules found within
the blood including -2-macroglobulin, resulting
in the formulation of an -2-macroglobulinprotease
complex. This newly formed complex
alters the molecular configuration of the -2-
macroglobulin molecule which results in a
change in its affinity to bind certain cytokines.
Once a cytokine is bound to the protease, the
entire complex is able to be eliminated from the
body, allowing normal cytokine balance and
immune function to be maintained.
Wobenzym® PS tablets are enteric coated to ensure
that the enzymes are protected and are not broken
down in the stomach. This allows the enzymes to
reach the small intestine where absorption can
Wobenzym® PS may be a useful dietary
supplement for individuals wishing to support
healthy joint, immune and circulatory function.
Warning: If you are pregnant or breastfeeding,
suffering from bleeding disorders or liver damage,
or if you are taking anticoagulant drugs (such as
warfarin), consult a healthcare professional before
using this product.
Store in a cool, dry place, away from direct light.
Keep out of reach of children.
Biziulevicius GA. Where do the immunostimulatory effects of
oral proteolytic enzymes ('systemic enzyme therapy') come
from? Microbial proteolysis as a possible starting point. Med
Klein G, Kullich W, Schnitker J, Schwann H. Efficacy and
tolerance of an oral enzyme combination in painful
osteoarthritis of the hip. A double-blind, randomised study
comparing oral enzymes with non-steroidal anti-inflammatory
drugs. Clin Exp Rheumatol. 2006 Jan-Feb;24(1):25-30.
Akhtar NM, Naseer R, Farooqi AZ, Aziz W, Nazir M. Oral
enzyme combination versus diclofenac in the treatment of
osteoarthritis of the knee--a double-blind prospective
randomized study. Clin Rheumatol. 2004 Oct;23(5):410-5.
Kamenícek V, Holán P, Frank P. [Systemic enzyme
therapy in the treatment and prevention of post-traumatic
and postoperative swelling] [Article in Czech] Acta Chir
Orthop Traumatol Cech. 2001;68(1):45-9.
Shahid SK, Turakhia NH, Kundra M, Shanbag P, Daftary
GV, Schiess W. Efficacy and safety of phlogenzym--a
protease formulation, in sepsis in children. J Assoc
Physicians India. 2002 Apr;50:527-31.
Singer F; Singer C ;Oberleitner H. Phlogenzym® versus
diclofenac in the treatment of activated osteoarthritis of the
knee. A double-blind prospective randomized study.
International Journal of Immunotherapy.2001:17,(2-4): 135-
Tilwe GH, Beria S, Turakhia NH, Daftary GV, Schiess W.
Efficacy and tolerability of oral enzyme therapy as compared
to diclofenac in active osteoarthrosis of knee joint: an open
randomized controlled clinical trial. J Assoc Physicians India.
Wittenborg A, Bock PR, Hanisch J, Saller R, Schneider B.
[Comparative epidemiological study in patients with
rheumatic diseases illustrated in a example of a treatment
with non-steroidal anti- inflammatory drugs versus an oral
enzyme combination preparation] [Article in German]
Arzneimittelforschung. 2000 Aug;50(8):728-38
†These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.